Ivan Koludarov

Complete and accurate annotation of troublesome gene regions

Ivan Koludarov visiting from the Technical University of Munich's Department of Scientific Computing will present a workshop on genome annotation methods and their application to difficult to annotate multicopy gene families.

schedule Date & time
Date/time
1 Sep 2025 9:30am - 2 Sep 2025 4:30pm
person Speaker

Speakers

Ivan Koludarov, Department of Scientific Computing, Technical University of Munich
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Event series

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Daniel Dashevsky

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Description

Workshop announcement (final dates TBC)

With the ever-increasing ease of generating more and higher quality genomic data, annotation remains a fundamentally hard problem that stands between sequencing and insight.

Most annotation is carried out using automated, homology-based, tools. These programs struggle to properly recognize and characterize genes that do not have closely related sequences in reference databases and many of them are explicitly coded to ignore repetitive annotations. This leads to unusually poor results from standard annotation pipelines for novel genes, those that evolve rapidly at the sequence level, and multicopy gene families.

Ivan Koludarov

Ivan Koludarov is a Humboldt Research Fellow in the Technical University of Munich's Department of Scientific Computing and his research on venom genes lead him to confront these issues head on. His current research projects focus on the thorough and careful annotation of venom genes in high-quality genomes which enables him to examine the microsyntenic patterns of these gene families to reconstruct detailed evolutionary histories across narrow and broad taxonomic scales.

Ivan will be in Canberra in the second half of 2025 to present a 2-day workshop on his genome annotation methods and how to apply them generally to multicopy gene families which are difficult to annotate (not just venoms).  

Final dates, program and registration details will be available soon.

Location

Research School of Biology, ANU and CSIRO Black Mountain, Canberra

-35.2758848, 149.1142774

Partners & sponsors

Centre for Biodiversity Analysis

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